Authentication of food allergen quality by physicochemical and immunological methods
Identifieur interne : 001C36 ( Main/Exploration ); précédent : 001C35; suivant : 001C37Authentication of food allergen quality by physicochemical and immunological methods
Auteurs : A. I. Sancho [Royaume-Uni] ; K. Hoffmann-Sommergruber [Autriche] ; S. Alessandri [Italie] ; A. Conti [Italie] ; M. G. Giuffrida [Italie] ; P. Shewry [Royaume-Uni] ; B. M. Jensen [Danemark] ; P. Skov [Danemark] ; S. Vieths [Allemagne]Source :
- Clinical & Experimental Allergy [ 0954-7894 ] ; 2010-07.
Abstract
Purified allergens are required to detect cross‐contamination with other allergenic foods and to understand allergen interaction with other components of the food matrix. Pure allergens are also used for the diagnosis and treatment of food allergies. For example, serological methods are being developed to improve the quality of diagnosis, and to reduce the need for food challenge tests. In addition, recombinant allergens are being evaluated as candidate vaccines for safe and efficacious specific immunotherapy. Pure allergens are indispensable as reference materials for the calibration and standardization of methods between different laboratories and operators for risk assessment in the food industry. Therefore, there is a need for well‐defined purified food allergens. In this context, a panel of 46 food allergens from plant and animal sources has been purified, from either the food sources or as recombinant forms, within the EU‐funded EuroPrevall project. These allergens have been characterized by a battery of diagnostic tests demonstrating that they constitute an authentic, well‐defined library of comparable quality. The review summarizes the applications, potentials and limitations of key techniques used for the characterization and authentication of these allergen preparations, with a special emphasis on protein purity and identity, folding, post‐translational modifications and immunochemical properties. One key area identified is the development of powerful analytical techniques, such as mass spectrometry and nuclear magnetic resonance, to improve the authentication of allergens for routine applications in allergy management. Cite this as: A. I. Sancho, K. Hoffmann‐Sommergruber, S. Alessandri, A. Conti, M. G. Giuffrida, P. Shewry, B. M. Jensen, P. Skov and S. Vieths, Clinical & Experimental Allergy, 2010 (40) 973–986.
Url:
DOI: 10.1111/j.1365-2222.2010.03534.x
Affiliations:
- Allemagne, Autriche, Danemark, Italie, Royaume-Uni
- Hovedstaden, Piémont, Vienne (Autriche)
- Copenhague, Turin, Vienne (Autriche)
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001730
- to stream Istex, to step Curation: 001729
- to stream Istex, to step Checkpoint: 000443
- to stream Main, to step Merge: 001C74
- to stream Main, to step Curation: 001C36
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Authentication of food allergen quality by physicochemical and immunological methods</title>
<author><name sortKey="Sancho, A I" sort="Sancho, A I" uniqKey="Sancho A" first="A. I." last="Sancho">A. I. Sancho</name>
</author>
<author><name sortKey="Hoffmann Ommergruber, K" sort="Hoffmann Ommergruber, K" uniqKey="Hoffmann Ommergruber K" first="K." last="Hoffmann-Sommergruber">K. Hoffmann-Sommergruber</name>
</author>
<author><name sortKey="Alessandri, S" sort="Alessandri, S" uniqKey="Alessandri S" first="S." last="Alessandri">S. Alessandri</name>
</author>
<author><name sortKey="Conti, A" sort="Conti, A" uniqKey="Conti A" first="A." last="Conti">A. Conti</name>
</author>
<author><name sortKey="Giuffrida, M G" sort="Giuffrida, M G" uniqKey="Giuffrida M" first="M. G." last="Giuffrida">M. G. Giuffrida</name>
</author>
<author><name sortKey="Shewry, P" sort="Shewry, P" uniqKey="Shewry P" first="P." last="Shewry">P. Shewry</name>
</author>
<author><name sortKey="Jensen, B M" sort="Jensen, B M" uniqKey="Jensen B" first="B. M." last="Jensen">B. M. Jensen</name>
</author>
<author><name sortKey="Skov, P" sort="Skov, P" uniqKey="Skov P" first="P." last="Skov">P. Skov</name>
</author>
<author><name sortKey="Vieths, S" sort="Vieths, S" uniqKey="Vieths S" first="S." last="Vieths">S. Vieths</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:6994CBB1170D6A64BBFC0B2E2A59445712CFE344</idno>
<date when="2010" year="2010">2010</date>
<idno type="doi">10.1111/j.1365-2222.2010.03534.x</idno>
<idno type="url">https://api.istex.fr/document/6994CBB1170D6A64BBFC0B2E2A59445712CFE344/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001730</idno>
<idno type="wicri:Area/Istex/Curation">001729</idno>
<idno type="wicri:Area/Istex/Checkpoint">000443</idno>
<idno type="wicri:doubleKey">0954-7894:2010:Sancho A:authentication:of:food</idno>
<idno type="wicri:Area/Main/Merge">001C74</idno>
<idno type="wicri:Area/Main/Curation">001C36</idno>
<idno type="wicri:Area/Main/Exploration">001C36</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Authentication of food allergen quality by physicochemical and immunological methods</title>
<author><name sortKey="Sancho, A I" sort="Sancho, A I" uniqKey="Sancho A" first="A. I." last="Sancho">A. I. Sancho</name>
<affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Food Research, Norwich</wicri:regionArea>
<wicri:noRegion>Norwich</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hoffmann Ommergruber, K" sort="Hoffmann Ommergruber, K" uniqKey="Hoffmann Ommergruber K" first="K." last="Hoffmann-Sommergruber">K. Hoffmann-Sommergruber</name>
<affiliation wicri:level="3"><country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Pathophysiology, Medical University of Vienna, Vienna</wicri:regionArea>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alessandri, S" sort="Alessandri, S" uniqKey="Alessandri S" first="S." last="Alessandri">S. Alessandri</name>
<affiliation wicri:level="1"><country xml:lang="fr">Italie</country>
<wicri:regionArea>Consorzio Interuniversitario Risonanze Magnetiche di Metalloproteine Paramagnetiche and Department of Agricultural Biotechnology, University of Florence, Florence</wicri:regionArea>
<wicri:noRegion>Florence</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Conti, A" sort="Conti, A" uniqKey="Conti A" first="A." last="Conti">A. Conti</name>
<affiliation wicri:level="3"><country xml:lang="fr">Italie</country>
<wicri:regionArea>CNR‐ISPA, Turin</wicri:regionArea>
<placeName><settlement type="city">Turin</settlement>
<region type="région" nuts="2">Piémont</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Giuffrida, M G" sort="Giuffrida, M G" uniqKey="Giuffrida M" first="M. G." last="Giuffrida">M. G. Giuffrida</name>
<affiliation wicri:level="3"><country xml:lang="fr">Italie</country>
<wicri:regionArea>CNR‐ISPA, Turin</wicri:regionArea>
<placeName><settlement type="city">Turin</settlement>
<region type="région" nuts="2">Piémont</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Shewry, P" sort="Shewry, P" uniqKey="Shewry P" first="P." last="Shewry">P. Shewry</name>
<affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Rothamsted Research, Harpenden</wicri:regionArea>
<wicri:noRegion>Harpenden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jensen, B M" sort="Jensen, B M" uniqKey="Jensen B" first="B. M." last="Jensen">B. M. Jensen</name>
<affiliation wicri:level="3"><country xml:lang="fr">Danemark</country>
<wicri:regionArea>Allergy Clinic, Copenhagen University Hospital, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Skov, P" sort="Skov, P" uniqKey="Skov P" first="P." last="Skov">P. Skov</name>
<affiliation wicri:level="3"><country xml:lang="fr">Danemark</country>
<wicri:regionArea>RefLab, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vieths, S" sort="Vieths, S" uniqKey="Vieths S" first="S." last="Vieths">S. Vieths</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Allergology, Paul‐Ehrlich‐Institut, Langen</wicri:regionArea>
<wicri:noRegion>Langen</wicri:noRegion>
<wicri:noRegion>Langen</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Clinical & Experimental Allergy</title>
<idno type="ISSN">0954-7894</idno>
<idno type="eISSN">1365-2222</idno>
<imprint><publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="2010-07">2010-07</date>
<biblScope unit="volume">40</biblScope>
<biblScope unit="issue">7</biblScope>
<biblScope unit="page" from="973">973</biblScope>
<biblScope unit="page" to="986">986</biblScope>
</imprint>
<idno type="ISSN">0954-7894</idno>
</series>
<idno type="istex">6994CBB1170D6A64BBFC0B2E2A59445712CFE344</idno>
<idno type="DOI">10.1111/j.1365-2222.2010.03534.x</idno>
<idno type="ArticleID">CEA3534</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0954-7894</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Purified allergens are required to detect cross‐contamination with other allergenic foods and to understand allergen interaction with other components of the food matrix. Pure allergens are also used for the diagnosis and treatment of food allergies. For example, serological methods are being developed to improve the quality of diagnosis, and to reduce the need for food challenge tests. In addition, recombinant allergens are being evaluated as candidate vaccines for safe and efficacious specific immunotherapy. Pure allergens are indispensable as reference materials for the calibration and standardization of methods between different laboratories and operators for risk assessment in the food industry. Therefore, there is a need for well‐defined purified food allergens. In this context, a panel of 46 food allergens from plant and animal sources has been purified, from either the food sources or as recombinant forms, within the EU‐funded EuroPrevall project. These allergens have been characterized by a battery of diagnostic tests demonstrating that they constitute an authentic, well‐defined library of comparable quality. The review summarizes the applications, potentials and limitations of key techniques used for the characterization and authentication of these allergen preparations, with a special emphasis on protein purity and identity, folding, post‐translational modifications and immunochemical properties. One key area identified is the development of powerful analytical techniques, such as mass spectrometry and nuclear magnetic resonance, to improve the authentication of allergens for routine applications in allergy management. Cite this as: A. I. Sancho, K. Hoffmann‐Sommergruber, S. Alessandri, A. Conti, M. G. Giuffrida, P. Shewry, B. M. Jensen, P. Skov and S. Vieths, Clinical & Experimental Allergy, 2010 (40) 973–986.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Autriche</li>
<li>Danemark</li>
<li>Italie</li>
<li>Royaume-Uni</li>
</country>
<region><li>Hovedstaden</li>
<li>Piémont</li>
<li>Vienne (Autriche)</li>
</region>
<settlement><li>Copenhague</li>
<li>Turin</li>
<li>Vienne (Autriche)</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><noRegion><name sortKey="Sancho, A I" sort="Sancho, A I" uniqKey="Sancho A" first="A. I." last="Sancho">A. I. Sancho</name>
</noRegion>
<name sortKey="Shewry, P" sort="Shewry, P" uniqKey="Shewry P" first="P." last="Shewry">P. Shewry</name>
</country>
<country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Hoffmann Ommergruber, K" sort="Hoffmann Ommergruber, K" uniqKey="Hoffmann Ommergruber K" first="K." last="Hoffmann-Sommergruber">K. Hoffmann-Sommergruber</name>
</region>
</country>
<country name="Italie"><noRegion><name sortKey="Alessandri, S" sort="Alessandri, S" uniqKey="Alessandri S" first="S." last="Alessandri">S. Alessandri</name>
</noRegion>
<name sortKey="Conti, A" sort="Conti, A" uniqKey="Conti A" first="A." last="Conti">A. Conti</name>
<name sortKey="Giuffrida, M G" sort="Giuffrida, M G" uniqKey="Giuffrida M" first="M. G." last="Giuffrida">M. G. Giuffrida</name>
</country>
<country name="Danemark"><region name="Hovedstaden"><name sortKey="Jensen, B M" sort="Jensen, B M" uniqKey="Jensen B" first="B. M." last="Jensen">B. M. Jensen</name>
</region>
<name sortKey="Skov, P" sort="Skov, P" uniqKey="Skov P" first="P." last="Skov">P. Skov</name>
</country>
<country name="Allemagne"><noRegion><name sortKey="Vieths, S" sort="Vieths, S" uniqKey="Vieths S" first="S." last="Vieths">S. Vieths</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/OrangerV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001C36 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001C36 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Bois |area= OrangerV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:6994CBB1170D6A64BBFC0B2E2A59445712CFE344 |texte= Authentication of food allergen quality by physicochemical and immunological methods }}
This area was generated with Dilib version V0.6.25. |